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Green Tea Extract Is Ineffective for Reducing Body Weight to Lower Prostate Cancer Risk

With more than one-third of U.S. adults considered to be obese and with the association between obesity and prostate cancer suggesting that obesity advances the disease, there is a need to find methods that can promote weight loss. A recent randomized, double-blind, placebo controlled trial evaluated the effectiveness of decaffeinated green tea catechins (GTC) on reducing body weight or abdominal obesity but failed to produce any decrease in anthropometric variables, including changes in weight, body mass index (BMI), and abdominal obesity.

“The obesity epidemic is stronger than ever and that underscores the importance of identifying effective alternatives for men at risk of prostate cancer to help them reduce their body weight,” stated Dr. David Samadi. “Even though green tea has numerous health benefits, as far as being an answer for effective weight management, there just doesn’t appear to be sufficient evidence to show this at this time.”

Several studies have suggested that obese men with high-grade prostatic intraepithelial neoplasia (HGPIN) are more prone to experiencing advances in prostate carcinogenesis. One study found men with metabolic syndrome(abdominal obesity, hypertension, and insulin resistance) who had HGPIN at their prostate biopsy were at a higher risk for prostate cancer. HGPIN is a common histological findings on prostate biopsy and is considered to be a precursor lesion and predictor of prostate cancer.

“Americans are always looking for ways to lose weight and many turn to using nutrient supplements in a pill form as their answer,” exclaimed Dr. Samadi. “Green tea is a popular beverage and has a couple of ingredients reported to be useful in weight management – caffeine and catechins. Green tea catechins have been extensively studied on their anti-cancer mechanisms in prostate carcinogenesis but it has also been proposed that the green tea catechins may reduce body weight by increasing energy expenditure and fat oxidation, along with reducing lipogenesis and decreasing fat absorption. And that is what this study wanted to find out – could green tea catechins not only reduce the progression of HGPIN but also induce weight loss resulting in a reduction of BMI, and waist to hip ratio. If it could, it would be one method of helping the overall reduction of prostate cancer risk in men with HGPIN.”

For the study, 97 men diagnosed with HGPIN were randomized to receive either 400 mg of bioactive catechins found in green tea or a placebo for one year. Anthropometric data were collected at baseline, 6 and 12 months with the data then being analyzed to observe any changes in body weight, BMI, and waist to hip ratio which is an indicator of abdominal obesity. Results from the study at one year showed men randomized into the group receiving decaffeinated green tea catechins tolerated it well but it was not effective in reducing any of the biomarkers for obesity.

“I believe the takeaway from this study is that men who are obese and at high risk for prostate cancer should avoid using nutritional supplements in hopes of it effectively reducing their body weight,” advised Dr. Samadi. “Green tea can still be enjoyed and used by these men but what really helps men most is screening for obesity. When we target those who are at a high risk for prostate cancer based on their risk factors such as their age, family history, or body weight, then we are making it a high priority to find interventions in helping them reach a healthier body weight. Instead of using ineffective means such as taking supplements, rather we should focus on more effective weight management techniques such as improving food choices and helping them develop a regular, consistent exercise routine. This is what will be more advantageous in improving their odds of reducing their risk of prostate cancer in the long run.”

Patients newly diagnosed with prostate cancer can contact world renowned prostate cancer surgeon and urologic oncologist, Dr. David Samadi, for a free phone consultation and to learn more about prostate cancer risk call 212-365-5000.

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* The benefits of robotic surgery cannot be guaranteed as surgery is both patient and procedure specific. Previous surgical results do not guarantee future outcomes.

Rita D., USA

It was Dr. Samadi himself wanting to speak with both of us to find out exactly what we needed and how he could help us. Dr. Samadi was a true hero in this story. I love him for what he did and would recommend him to anyone who has been diagnosed with prostate cancer.

Jose M. C., Colombia

Siempre recordare el 2009 como el mas tragico de mi vida ; sin presentar sintomas y a raiz de mi examen anual de salud me fue detectado un cancer de prostata, la intuicion de mi medico personal al ver mi psa en 3.4 lo hizo referirme al urologo para que me practicase una biopsia , el mundo se me vino encima.

Martin K,

Earlier this year I was given the devastating news that I had prostate cancer.  I was diagnosed after a routine company medical, followed by a Biopsy.  From that day and during the following weeks I researched the subject to try and find a subtitle course of treatment...

Len F.

On Oct. 1, 2009, I was diagnosed with prostate cancer.  I had anticipated that the biopsy findings would be negative and I was rather shocked with this diagnosis.