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Is Blood in Urine a Sign of Prostate Cancer?

May 23, 2025
In this guide, Dr. David B. Samadi, world-renowned urologist and prostate cancer expert, breaks down the possible causes of hematuria and when it could be a warning sign of prostate cancer.

What Is Hematuria?

Hematuria refers to the presence of blood in the urine and can appear in two forms:

  • Gross hematuria: Blood is visible to the naked eye—your urine may appear pink, red, or tea-colored.

  • Microscopic hematuria: Blood is only detectable under a microscope during a urine test.

While gross hematuria is more noticeable and alarming, both types warrant medical evaluation, especially if they occur more than once.

Can Prostate Cancer Cause Blood in Urine?

Yes—but it’s not common. While prostate cancer can cause hematuria, especially in advanced stages, it is not typically an early symptom. When prostate cancer does lead to blood in the urine, it’s usually because the tumor has grown enough to:

  • Invade nearby structures like the urethra or bladder

  • Disrupt blood vessels in the prostate

  • Cause inflammation or obstruction

In most cases, elevated PSA levels or urinary symptoms (like frequent urination or weak flow) show up long before hematuria.

Other Causes of Blood in Urine

Many conditions—most of them not cancer—can lead to blood in the urine. These include:

  • Urinary tract infections (UTIs)

  • Kidney stones

  • Bladder or kidney infections

  • Enlarged prostate (BPH)

  • Prostatitis (prostate inflammation)

  • Vigorous exercise

  • Certain medications (e.g., blood thinners)

That’s why it’s important to be evaluated by a specialist who can determine the root cause through testing and imaging.

When to See a Urologist

You should make an appointment with a urologist if you notice:

  • Visible blood in your urine (even once)

  • Frequent urination or pain during urination

  • Difficulty starting or stopping your urine stream

  • A history of elevated PSA levels

  • Urinary retention or changes in bladder control

Even if your symptoms seem mild, early evaluation can lead to early treatment—and better outcomes.

How Is Hematuria Evaluated?

Dr. Samadi uses a comprehensive approach to diagnose the cause of blood in the urine. This typically includes:

  1. Urinalysis and urine culture – to check for infection or microscopic blood

  2. PSA blood test – to assess for prostate issues

  3. Digital rectal exam (DRE) – to check prostate texture and size

  4. Imaging (CT scan, ultrasound, or MRI) – to evaluate kidneys, bladder, and prostate

  5. Cystoscopy – a visual exam of the bladder and urethra using a small scope

Each step helps pinpoint the exact cause so the appropriate treatment plan can be developed.

Is Hematuria Ever an Emergency?

Yes. You should seek immediate medical attention if you experience:

  • Blood in urine accompanied by fever or chills

  • Severe pain in your back or lower abdomen

  • Difficulty urinating or inability to urinate

  • Blood clots in urine that affect flow

These could indicate an infection, kidney stone, or severe obstruction.

Expert Evaluation From Dr. David B. Samadi

Dr. Samadi understands how stressful it can be to see blood in your urine. As a leading urologist, he provides thorough diagnostic care using the most advanced tools available. Whether your symptoms are caused by an infection, prostate enlargement, or something more serious, you’ll receive a clear diagnosis and a personalized plan for treatment.

Concerned About Blood in Your Urine? Don’t Wait.

If you’ve noticed blood in your urine or are experiencing other urinary changes, it’s time to get answers. Dr. David B. Samadi can help you take the next step with confidence.